GQW articles: February 2012 edition

Following is a list of articles related to G-quadruplex research published (for the first time on the web or “officially” in print) during the month of February 2012. This post includes 14 articles divided by category as follows:

• GQ-Biology (GQB).  6 articles
• GQ-Cations (GQC). 1 articles
• GQ-Methods (GQM). 1 articles
• GQ-Nano & Technology (GQNT). 3 articles
• GQ-Recognition (GQR). 2 articles
• GQ-Structure & Dynamics (GQSD). 1 articles
• GQ-Supramolecular (GQS). 0 article

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• GQ-Biology. Studies aimed at the discovery of GQs in living organisms and the elucidation of their role in biological processes. (putative quadruplex sequences in genomes; proteins that recognize GQs; in vitro and in vivo studies of GQs) [6 articles]

1. Charge and substituent effects on the stability of porphyrin/G-quadruplex adducts. Ramos CI, Tomé JP, Santana-Marques MG. J Mass Spectrom. 2012 Feb;47(2):173-179. doi: 10.1002/jms.2048. PMID: 22359326
2. Self-entanglement of long linear DNA vectors using transient non-B-DNA attachment points: A new concept for improvement of non-viral therapeutic gene delivery. Tolmachov OE. Med Hypotheses. 2012 Feb 20. [Epub before print] PMID: 22356834
3.  5′-UTR RNA G-quadruplexes: translation regulation and targeting. [OA] Bugaut A, Balasubramanian S. Nucleic Acids Res. 2012 Feb 20. [Epub before print] PMID: 22351747
4. A telomerase-associated RecQ protein-like helicase resolves telomeric G-quadruplex structures during replication. Postberg J, Tsytlonok M, Sparvoli D, Rhodes D, Lipps HJ. Gene. 2012 Feb 2. [Epub before print] PMID: 22327026
5. New insights into replication origin characteristics in metazoans. [OA] Cayrou C, Coulombe P, Puy A, Rialle S, Kaplan N, Segal E, Méchali M. Cell Cycle. 2012 Feb 15; 11 (4). PMID: 22307000
6. A G-Rich Element Forms a G-Quadruplex and Regulates Bace1 mRNA Alternative Splicing. Fisette JF, Montagna DR, Mihailescu MR, Wolfe MS. J Neurochem. 2012 Feb 3. [Epub before print] doi: 10.1111/j.1471-4159.2012.07680.x. PMID: 22303960

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• GQ-Cations. Studies aimed at elucidating the role of cations in GQ structure and/or dynamics. [1 articles]

1. Cation binding to 15-TBA quadruplex DNA is a multiple-pathway cation-dependent process. [OA] Reshetnikov RV, Sponer J, Rassokhina OI, Kopylov AM, Tsvetkov PO, Makarov AA, Golovin AV. Nucleic Acids Res. 2011 Dec;39 (22):9789-9802. Epub 2011 Sep 5. PMID: 21893589

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• GQ-Methods. Application and development of methods and techniques to study GQs. [1 articles]

1.  Experimental approaches to identify cellular G-quadruplex structures and functions. Antonio MD, Rodriguez R, Balasubramanian S. Methods. 2012 Feb 11. [Epub before print] PMID: 22343041

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• GQ-Nano & Technology. The design and development of GQ-based nanostructures. The use of GQs as components in devices (e.g., sensors). [3 articles]

1. Following Glucose Oxidase Activity by Chemiluminescence and Chemiluminescence Resonance Energy Transfer (CRET) Processes Involving Enzyme-DNAzyme Conjugates. [OA] Niazov A, Freeman R, Girsh J, Willner I. Sensors. 2011;11(11):10388-97. Epub 2011 Oct 31. PMID: 22346648
2. A label-free G-quadruplex-based switch-on fluorescence assay for the selective detection of ATP. He HZ, Pui-Yan Ma V, Leung KH, Shiu-Hin Chan D, Yang H, Cheng Z, Leung CH, Ma DL. Analyst. 2012 Feb 20. [Epub before print] PMID: 22343772
3. A novel biosensing strategy for screening G-quadruplex ligands based on graphene oxide sheets. Wang H, Chen T, Wu S, Chu X, Yu R. Biosens Bioelectron. 2012 Jan 26. [Epub before print] PMID: 22336439

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• GQ-Recognition. Discovery and development of (mostly) small molecule ligands that recognize GQs (synthesis; design; pharmacology; medicinal chemistry). [2 articles]

1. Small-molecule-induced DNA damage identifies alternative DNA structures in human genes. Rodriguez R, Miller KM, Forment JV, Bradshaw CR, Nikan M, Britton S, Oelschlaegel T, Xhemalce B, Balasubramanian S, Jackson SP. Nat Chem Biol. 2012 Feb 5. doi: 10.1038/nchembio.780 [Epub before print] PMID: 22306580
2.  Alternative DNA structures: G4 DNA in cells: itae missa est? Jean-Louis Mergny. Nature Chemical Biology 8, 225–226 (2012) doi:10.1038/nchembio.793 Published online 15 February 2012

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• GQ-Structure & Dynamics. Studies aimed at elucidating structure and/or dynamics GQ. This includes experimental techniques such as X-Ray crystallography, NMR, and other spectroscopic methods as well as theoretical approaches such as MD-simulations. [1 articles]

1.  Unique structural features of interconverting monomeric and dimeric G-quadruplexes adopted by a sequence from intron of N-myc gene. Trajkovski M, Webba da Silva M, Plavec J. J Am Chem Soc. 2012 Feb 3. [Epub before print] PMID: 22303871

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• GQ-Supramolecular. Studies related to the design and applications of GQs in supramolecular chemistry. (assemblies; molecular devices) [0 articles]

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[OA] = Open Access

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